The Vatican is a treasure trove of art, architecture and rarities. This is but one of millions, Gabinetto Del Laocoonte or Laocoön and His Sons; from Wikipaedia:

The statue is attributed by the Roman author Pliny the Elder to three sculptors from the island of Rhodes: Agesander, Athenodoros and Polyclitus. It shows the Trojan priest Laocoön and his sons Antiphantes and Thymbraeus being strangled by sea serpents.

Given the modern trappings wrapping around almost any landmark that sites right smack in the middle of an urban center, it's no surprise that getting a picture of an ancient site is "challenging" and this one, shot on the run, isn't as successful as I'd like. However, I think it still works to show how imposing a structure the Roman Coliseum really is. I guess I'll have to go back and try again, I suppose.